Granger causality network reconstruction of conductance-based integrate-and-fire neuronal systems.

ABSTRACT: Reconstruction of anatomical connectivity from measured dynamical activities of coupled neurons is one of the fundamental issues in the understanding of structure-function relationship of neuronal circuitry. Many approaches have been developed to address this issue based on either electrical or metabolic data observed in experiment. The Granger causality (GC) analysis remains one of the major approaches to explore the dynamical causal connectivity among individual neurons or neuronal populations. However, it is yet to be clarified how such causal connectivity, i.e., the GC connectivity, can be mapped to the underlying anatomical connectivity in neuronal networks. We perform the GC analysis on the conductance-based integrate-and-fire (I&F) neuronal networks to obtain their causal connectivi

SUBMITTER: Zhou D 

PROVIDER: S-EPMC3929548 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature