Rectoanal reflexes and sensorimotor response in rectal hyposensitivity.

ABSTRACT:

Purpose

Rectal hyposensitivity commonly causes anorectal disorders, but its underlying mechanism is unknown. We hypothesized that subjects with rectal hyposensitivity have altered rectoanal reflexes and/or sensorimotor response.

Methods

We performed stepwise graded balloon distensions of the rectum in 30 subjects with constipation and rectal hyposensitivity and in 23 healthy controls. Thresholds for first sensation, desire, and urgency to defecate were assessed. The lowest balloon volume that evoked rectoanal inhibitory reflex, rectoanal contractile reflex, and sensorimotor response and manometric characteristics and rectal compliance were examined.

Results

Reflex responses were present in all subjects. The balloon volumes were higher in subjects with rectal hyposensi

SUBMITTER: Remes-Troche JM 

PROVIDER: S-EPMC3929945 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature