Frailty and depression in older adults: a high-risk clinical population.

ABSTRACT:

Objective

To identify salient characteristics of frailty that increase risk of death in depressed elders.

Methods

Data were from the Nordic Research on Ageing Study from research sites in Denmark, Sweden, and Finland. Participants were 1,027 adults aged 75 years (436 men and 591 women). Time of death was obtained, providing a maximum survival time of 11.08 years (initial evaluation took place between 1988 and 1991).

Results

Depressed elders showed greater baseline impairments in each frailty characteristic (gait speed, grip strength, physical activity levels, and fatigue). Simultaneous models including all four frailty characteristics showed slow gait speed (hazard ratio: 1.84; 95% confidence interval: 1.05-3.21) and fatigue (hazard ratio: 1.94; 95% confidence interva

SUBMITTER: Brown PJ 

PROVIDER: S-EPMC3930630 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature