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Real-world cost-effectiveness: lower cost of treating patients to glycemic goal with liraglutide versus exenatide.


ABSTRACT:

Introduction

While the liraglutide effect and action in diabetes (LEAD-6) clinical trial compared the efficacy and safety of liraglutide once daily (LIRA) to exenatide twice daily (EXEN) in adult patients with type 2 diabetes, few studies have explored the associated per-patient costs of glycemic goal achievement of their use in a real-world clinical setting.

Methods

This retrospective cohort study used integrated medical and pharmacy claims linked with glycated hemoglobin A1C (A1C) results from the IMS Patient-Centric Integrated Data Warehouse. Patients' ≥18 years and naïve to incretin therapies during a 6-month pre-index period, with ≥1 prescription for LIRA or EXEN between January 2010 and December 2010, were included. Patients with evidence of insulin use (pre- or post-i

SUBMITTER: DeKoven M 

PROVIDER: S-EPMC3930836 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature