Simple noninvasive systems predict long-term outcomes of patients with nonalcoholic fatty liver disease.

ABSTRACT:

Background & aims

Some patients with nonalcoholic fatty liver disease (NAFLD) develop liver-related complications and have higher mortality than other patients with NAFLD. We determined the accuracy of simple, noninvasive scoring systems in identification of patients at increased risk for liver-related complications or death.

Methods

We performed a retrospective, international, multicenter cohort study of 320 patients diagnosed with NAFLD, based on liver biopsy analysis through 2002 and followed through 2011. Patients were assigned to mild-, intermediate-, or high-risk groups based on cutoff values for 2 of the following: NAFLD fibrosis score, aspartate aminotransferase/platelet ratio index, FIB-4 score, and BARD score. Outcomes included liver-related complications and death

SUBMITTER: Angulo P 

PROVIDER: S-EPMC3931256 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature