Determination of nitrite in saliva using microfluidic paper-based analytical devices.

ABSTRACT: Point-of-care platforms can provide fast responses, decrease the overall cost of the treatment, allow for in-home determinations with or without a trained specialist, and improve the success of the treatment. This is especially true for microfluidic paper-based analytical devices (μPAD), which can enable the development of highly efficient and versatile analytical tools with applications in a variety of biomedical fields. The objective of this work was the development of μPADs to identify and quantify levels of nitrite in saliva, which has been proposed as a potential marker of periodontitis. The devices were fabricated by wax printing and allowed the detection of nitrite by a colorimetric reaction based on a modified version of the Griess reaction. The presented modifications, along with

SUBMITTER: Bhakta SA 

PROVIDER: S-EPMC3931572 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature