The relationship between pre-eclampsia and peripartum cardiomyopathy: a systematic review and meta-analysis.

ABSTRACT:

Objectives

The goal of this study was to systematically review the peripartum cardiomyopathy (PPCM) literature and determine the prevalence of pre-eclampsia (PE) in women with PPCM. Secondary analyses included evaluation of the prevalence of hypertensive disorders, multiple gestations, and multiparity.

Background

PPCM is a significant cause of maternal and infant morbidity and mortality worldwide, yet its etiology remains unknown. PE is often cited as a risk factor for the development of PPCM and recent research suggests that PE and PPCM share mechanisms that contribute to their pathobiology. No comprehensive evaluation of the relationship between PE and PPCM exists.

Methods

A systematic predetermined search strategy was performed in multiple databases to identify stu

SUBMITTER: Bello N 

PROVIDER: S-EPMC3931606 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature