Association of serum periostin with cardiac function and short-term prognosis in acute myocardial infarction patients.

ABSTRACT:

Background

Periostin was proved to play an important role in extra-cellular matrix remodeling after acute myocardial infarction (AMI). Myocardial periostin was markedly up-regulated after AMI and participated in the maladaptive process of cardiac remodeling. However, few researches focused on the circulating periostin and its significance. This study aims to investigate the association of serum periostin level with cardiac function and short-term prognosis in AMI patients.

Methodology/principal findings

We totally recruited 50 patients diagnosed as ST-elevation myocardial infarction. Blood samples were taken within 12 hours after the onset of AMI before emergency coronary revascularization procedures. Serum periostin was measured using enzyme-linked immunosorbent assay. All

SUBMITTER: Ling L 

PROVIDER: S-EPMC3931651 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature