Molecular epidemiology of human enterovirus associated with aseptic meningitis in Shandong Province, China, 2006-2012.

ABSTRACT:

Background

Human enteroviruses (HEVs) are common causes of acute meningitis. However, there is limited information about HEV associated with aseptic meningitis in mainland China because it has not been classified as a notifiable disease.

Objectives

To characterize the HEVs associated with sporadic aseptic meningitis in China and to analyze their genetic features.

Study design

Cerebrospinal fluid, throat swab and feces specimens were collected from patients with aseptic meningitis in 5 sentinel hospitals in Shandong Province, China between 2006 and 2012. Virological investigation (viral isolation and molecular identification) and phylogenetic analysis were performed.

Results

A total of 437 hospitalized patients were reported, and enteroviruses were detected in t

SUBMITTER: Tao Z 

PROVIDER: S-EPMC3931826 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature