Should patients with acute coronary disease be stratified for management according to their risk? Derivation, external validation and outcomes using the updated GRACE risk score.

ABSTRACT:

Objectives

Risk scores are recommended in guidelines to facilitate the management of patients who present with acute coronary syndromes (ACS). Internationally, such scores are not systematically used because they are not easy to apply and some risk indicators are not available at first presentation. We aimed to derive and externally validate a more accurate version of the Global Registry of Acute Coronary Events (GRACE) risk score for predicting the risk of death or death/myocardial infarction (MI) both acutely and over the longer term. The risk score was designed to be suitable for acute and emergency clinical settings and usable in electronic devices.

Design and setting

The GRACE risk score (2.0) was derived in 32 037 patients from the GRACE registry (14 countries, 94 hosp

SUBMITTER: Fox KA 

PROVIDER: S-EPMC3931985 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature