The neural and genetic basis of executive function: attention, cognitive flexibility, and response inhibition.

ABSTRACT: Executive function is a collection of cognitive processes essential for higher order mental function. Processes involved in executive function include, but are not limited to, working memory, attention, cognitive flexibility, and impulse control. These complex behaviors are largely mediated by prefrontal cortical function but are modulated by dopaminergic, noradrenergic, serotonergic, and cholinergic input. The ability of these neurotransmitter systems to modulate executive function allows for adaptation in cognitive behavior in response to changes in the environment. Because of the important role these neurotransmitter systems play in regulating executive function, changes in these systems can also have a grave impact on executive function. In addition, polymorphisms in genes associated w

SUBMITTER: Logue SF 

PROVIDER: S-EPMC3933483 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature