Outbreak of febrile respiratory illness associated with human adenovirus type 14p1 in Gansu Province, China.

ABSTRACT:

Objectives

Human adenovirus (HAdV) type 14 had been infrequently associated with outbreaks of febrile respiratory illness (FRI) until the HAdV-14p1 emerged in 2006 and rapidly spread in the United States. Here, we report an outbreak of FRI caused by HadV-14p1 that occurred in 2011 at a primary and middle school in China.

Design

The basic information of the outbreak was recored; throat swabs were collected from 17 patients, polymerase chain reaction, A549 cell culture, and sequencing were used to identify the pathogen of the outbreak..

Results

Total of 43 students were infected in this outbreak. Boys were more than girls. We identified 11 HAdV-positive specimens and 6 HAdV isolates. Genetic analysis showed that the complete hexon, fiber, and E1A sequences of isolates w

SUBMITTER: Huang G 

PROVIDER: S-EPMC3933759 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature