Biopsy of the superficial cortex: predictors of effectiveness and outcomes.

ABSTRACT:

Background

Brain biopsies of superficial cortex are performed for diagnosis of neurological diseases, but preoperative predictors of successful diagnosis and risks are lacking.

Objective

We evaluated effectiveness and outcomes of superficial cortical biopsies and determined preoperative predictors of diagnosis, outcomes, morbidities, and mortality.

Methods

A single-institution retrospective analysis of 170 patients who underwent open brain biopsies of superficial cortex was performed. Clinical predictors of effectiveness and outcomes were determined using univariate/multivariate analyses and a system for risk-benefit stratification was created and tested.

Results

Brain biopsies led to successful diagnosis in 122 of 170 (71.8%) and affected management in 97 of 1

SUBMITTER: Hawasli AH 

PROVIDER: S-EPMC3934358 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature