Ontology highlight
ABSTRACT:
SUBMITTER: Yang JY
PROVIDER: S-EPMC3936340 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Journal of natural products 20130911 9
A major goal in natural product discovery programs is to rapidly dereplicate known entities from complex biological extracts. We demonstrate here that molecular networking, an approach that organizes MS/MS data based on chemical similarity, is a powerful complement to traditional dereplication strategies. Successful dereplication with molecular networks requires MS/MS spectra of the natural product mixture along with MS/MS spectra of known standards, synthetic compounds, or well-characterized or ...[more]