Novel relationship of serum cholesterol with asthma and wheeze in the United States.

ABSTRACT:

Background

Cholesterol exerts complex effects on inflammation. There has been little investigation of whether serum cholesterol is associated with asthma, an inflammatory airways disease with great public health impact.

Objective

To determine relationships between levels of 3 serum cholesterol measures (total cholesterol [TC], high-density lipoprotein cholesterol [HDL-C], and non-HDL-C) and asthma/wheeze in a sample representative of the US population.

Methods

Cross-sectional study of 7005 participants age >or=6 years from the 2005 to 2006 National Health and Nutrition Examination Survey.

Results

Serum TC and non-HDL-C were lower in patients with current asthma than in subjects without current asthma in the overall population (TC, 188.5 vs 192.2 mg/dL; non-HDL-

SUBMITTER: Fessler MB 

PROVIDER: S-EPMC3936400 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature