Mining locus tags in PubMed Central to improve microbial gene annotation.

ABSTRACT:

Background

The scientific literature contains millions of microbial gene identifiers within the full text and tables, but these annotations rarely get incorporated into public sequence databases. We propose to utilize the Open Access (OA) subset of PubMed Central (PMC) as a gene annotation database and have developed an R package called pmcXML to automatically mine and extract locus tags from full text, tables and supplements.

Results

We mined locus tags from 1835 OA publications in ten microbial genomes and extracted tags mentioned in 30,891 sentences in main text and 20,489 rows in tables. We identified locus tag pairs marking the start and end of a region such as an operon or genomic island and expanded these ranges to add another 13,043 tags. We also searched for locus t

SUBMITTER: Stubben CJ 

PROVIDER: S-EPMC3937057 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature