Genomic characteristics and comparative genomics analysis of Penicillium chrysogenum KF-25.

ABSTRACT:

Background

Penicillium chrysogenum has been used in producing penicillin and derived β-lactam antibiotics for many years. Although the genome of the mutant strain P. chrysogenum Wisconsin 54-1255 has already been sequenced, the versatility and genetic diversity of this species still needs to be intensively studied. In this study, the genome of the wild-type P. chrysogenum strain KF-25, which has high activity against Ustilaginoidea virens, was sequenced and characterized.

Results

The genome of KF-25 was about 29.9 Mb in size and contained 9,804 putative open reading frames (orfs). Thirteen genes were predicted to encode two-component system proteins, of which six were putatively involved in osmolarity adaption. There were 33 putative secondary metabolism pathways and numerou

SUBMITTER: Peng Q 

PROVIDER: S-EPMC3938070 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature