Risk factors for early childhood infection of human herpesvirus-8 in Zambian children: the role of early childhood feeding practices.

ABSTRACT:

Background

Human herpesvirus-8 (HHV-8) infection in early childhood is common throughout sub-Saharan Africa with prevalence increasing throughout childhood. Specific routes of transmission have not been clearly delineated, though HHV-8 is present in high concentrations in saliva.

Methods

To understand the horizontal transmission of HHV-8 within households to children, we enrolled for cross-sectional analysis, 251 households including 254 children, age two and under, in Lusaka, Zambia. For all children, plasma was screened for HHV-8 and HIV type I (HIV-1) and health and behavioral questionnaires were completed. Multilevel logistic regression analysis was conducted to assess independent factors for HHV-8 infection in children.

Results

Risk factors for HHV-8 infection in

SUBMITTER: Crabtree KL 

PROVIDER: S-EPMC3939055 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature