Role of statins in the development and progression of age-related macular degeneration.

ABSTRACT:

Purpose

To determine if statins are associated with the development or progression of age-related macular degeneration (AMD).

Methods

A large, national insurance claims database was reviewed to identify individuals aged 60 years or older who were enrolled for ≥2 years and had ≥1 visits to an eye provider. Prescription claims for statins within a 24-month look-back period and outpatient lipid laboratory values were also reviewed. Cox regression analysis was used to determine whether statin use was associated with the development of nonexudative or exudative AMD or progressing from nonexudative to exudative AMD.

Results

Of the 107,007 beneficiaries eligible for the nonexudative AMD analysis, 4,647 incident cases of nonexudative AMD occurred. Seven hundred and ninety-two

SUBMITTER: VanderBeek BL 

PROVIDER: S-EPMC3939714 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature