Hepatic dysfunction in ambulatory patients with heart failure: application of the MELD scoring system for outcome prediction.

ABSTRACT:

Objectives

This study evaluated the Model for End-Stage Liver Disease (MELD) score and its modified versions, which are established measures of liver dysfunction, as a tool to assess heart transplantation (HTx) urgency in ambulatory patients with heart failure.

Background

Liver abnormalities have a prognostic impact on the outcome of patients with advanced heart failure.

Methods

We retrospectively evaluated 343 patients undergoing HTx evaluation between 2005 and 2009. The prognostic effectiveness of MELD and 2 modifications (MELDNa [includes serum sodium levels] and MELD-XI [does not include international normalized ratio]) for endpoint events, defined as death/HTx/ventricular assist device requirement, was evaluated in our cohort and in subgroups of patients on and o

SUBMITTER: Kim MS 

PROVIDER: S-EPMC3939720 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature