Endometrial gene expression profiling in pregnant Meishan and Yorkshire pigs on day 12 of gestation.

ABSTRACT:

Background

Litter size in pigs is a major factor affecting the profitability in the pig industry. The peri-implantation window in pigs is characterized by the coordinated interactions between the maternal uterine endometrium and the rapidly elongating conceptuses and represents a period of time during which a large percentage of the developing conceptuses are lost. However, the gene expression and regulatory networks in the endometrium contributing to the establishment of the maternal: placental interface remain poorly understood.

Results

We characterized the endometrial gene expression profile during the peri-implantation stage of development by comparing two breeds that demonstrate very different reproductive efficiencies. We employed the porcine Affymetrix GeneChip® to as

SUBMITTER: Gu T 

PROVIDER: S-EPMC3940021 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature