Comparative genomics analysis of Lactobacillus species associated with weight gain or weight protection.

ABSTRACT:

Background

Some Lactobacillus species are associated with obesity and weight gain while others are associated with weight loss. Lactobacillus spp. and bifidobacteria represent a major bacterial population of the small intestine where lipids and simple carbohydrates are absorbed, particularly in the duodenum and jejunum. The objective of this study was to identify Lactobacillus spp. proteins involved in carbohydrate and lipid metabolism associated with weight modifications.

Methods

We examined a total of 13 complete genomes belonging to seven different Lactobacillus spp. previously associated with weight gain or weight protection. We combined the data obtained from the Rapid Annotation using Subsystem Technology, Batch CD-Search and Gene Ontology to classify gene function in

SUBMITTER: Drissi F 

PROVIDER: S-EPMC3940830 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature