Effects of risperidone and parent training on adaptive functioning in children with pervasive developmental disorders and serious behavioral problems.

ABSTRACT:

Objective

Children with Pervasive Developmental Disorders (PDDs) have social interaction deficits, delayed communication, and repetitive behaviors as well as impairments in adaptive functioning. Many children actually show a decline in adaptive skills compared with age mates over time.

Method

This 24-week, three-site, controlled clinical trial randomized 124 children (4 through 13 years of age) with PDDs and serious behavioral problems to medication alone (MED; n = 49; risperidone 0.5 to 3.5 mg/day; if ineffective, switch to aripiprazole was permitted) or a combination of medication plus parent training (PT) (COMB; n = 75). Parents of children in COMB received an average of 11.4 PT sessions. Standard scores and Age-Equivalent scores on Vineland Adaptive Behavior Scales were

SUBMITTER: Scahill L 

PROVIDER: S-EPMC3941712 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature