Risk of scar in the comparison of age-related macular degeneration treatments trials.

ABSTRACT:

Objective

To describe risk factors for scar in eyes treated with ranibizumab or bevacizumab for neovascular age-related macular degeneration (AMD).

Design

Prospective cohort study within a randomized clinical trial.

Participants

Patients with no scar on color fundus photography (CFP) or fluorescein angiography (FA) at enrollment in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT).

Methods

Eyes were assigned to ranibizumab or bevacizumab treatment and to 1 of 3 dosing regimens for 2 years. Masked readers assessed CFP and FA. Baseline demographic characteristics, visual acuity, morphologic features on photography and optical coherence tomography (OCT), and genotypes associated with AMD risk were evaluated as risk factors using adjusted

SUBMITTER: Daniel E 

PROVIDER: S-EPMC3943618 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature