Effects of prenatal community violence and ambient air pollution on childhood wheeze in an urban population.

ABSTRACT:

Background

Prenatal exposures to stress and physical toxins influence children's respiratory health, although few studies consider these factors together.

Objectives

We sought to concurrently examine the effects of prenatal community-level psychosocial (exposure to community violence [ECV]) and physical (air pollution) stressors on repeated wheeze in 708 urban children followed to age 2 years.

Methods

Multi-item ECV reported by mothers in pregnancy was summarized into a continuous score by using Rasch modeling. Prenatal black carbon exposure was estimated by using land-use regression (LUR) modeling; particulate matter with a diameter of less than 2.5 μm (PM2.5) was estimated by using LUR modeling incorporating satellite data. Mothers reported child's wheeze every 3 mo

SUBMITTER: Chiu YH 

PROVIDER: S-EPMC3943665 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature