The CO-Regulation Database (CORD): a tool to identify coordinately expressed genes.

ABSTRACT:

Background

Meta-analysis of gene expression array databases has the potential to reveal information about gene function. The identification of gene-gene interactions may be inferred from gene expression information but such meta-analysis is often limited to a single microarray platform. To address this limitation, we developed a gene-centered approach to analyze differential expression across thousands of gene expression experiments and created the CO-Regulation Database (CORD) to determine which genes are correlated with a queried gene.

Results

Using the GEO and ArrayExpress database, we analyzed over 120,000 group by group experiments from gene microarrays to determine the correlating genes for over 30,000 different genes or hypothesized genes. CORD output data is presente

SUBMITTER: Fahrenbach JP 

PROVIDER: S-EPMC3944024 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature