Detection and genetic characterization of Seoul virus from commensal brown rats in France.

ABSTRACT:

Background

Hantaviruses are single-stranded RNA viruses, which are transmitted to humans primarily via inhalation of aerosolised virus in contaminated rodent urine and faeces. Whilst infected reservoir hosts are asymptomatic, human infections can lead to two clinical manifestations, haemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS), with varying degrees of clinical severity. The incidence of rodent and human cases of Seoul virus (SEOV) in Europe has been considered to be low, and speculated to be driven by the sporadic introduction of infected brown rats (Rattus norvegicus) via ports.

Methods

Between October 2010 and March 2012, 128 brown rats were caught at sites across the Lyon region in France.

Results

SEOV RNA was detecte

SUBMITTER: Dupinay T 

PROVIDER: S-EPMC3944734 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature