Association of interleukin-10 polymorphisms with schizophrenia: a meta-analysis.

ABSTRACT:

Background

The involvement of cytokines in schizophrenia (SZ) has been proposed in recent years and various studies have accumulated convergent lines of evidence. Among which, the role of interleukin-10 (IL-10) in SZ has been explored in a number of studies by investigating association of single nucleotide polymorphisms (SNPs) and susceptibility of SZ. However, the results are inconsistent since its power is limited by the individual sample size. To evaluate the overall effect between them, we conducted a meta-analysis by combining all available studies.

Methods

Studies were searched from the database of PubMed, PsycINFO and ISI web of Knowledge up to Nov 2013. The meta-analysis was conducted based on statement of preferred reporting items for systematic reviews and meta-ana

SUBMITTER: Gao L 

PROVIDER: S-EPMC3946087 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature