Combined acquisition technique (CAT) for neuroimaging of multiple sclerosis at low specific absorption rates (SAR).

ABSTRACT:

Purpose

To compare a novel combined acquisition technique (CAT) of turbo-spin-echo (TSE) and echo-planar-imaging (EPI) with conventional TSE. CAT reduces the electromagnetic energy load transmitted for spin excitation. This radiofrequency (RF) burden is limited by the specific absorption rate (SAR) for patient safety. SAR limits restrict high-field MRI applications, in particular.

Material and methods

The study was approved by the local Medical Ethics Committee. Written informed consent was obtained from all participants. T2- and PD-weighted brain images of n = 40 Multiple Sclerosis (MS) patients were acquired by CAT and TSE at 3 Tesla. Lesions were recorded by two blinded, board-certificated neuroradiologists. Diagnostic equivalence of CAT and TSE to detect MS lesions was e

SUBMITTER: Biller A 

PROVIDER: S-EPMC3946656 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature