Human impacts have shaped historical and recent evolution in Aedes aegypti, the dengue and yellow fever mosquito.

ABSTRACT: Although anthropogenic impacts are often considered harmful to species, human modifications to the landscape can actually create novel niches to which other species can adapt. These "domestication" processes are especially important in the context of arthropod disease vectors, where ecological overlap of vector and human populations may lead to epidemics. Here, we present results of a global genetic study of one such species, the dengue and yellow fever mosquito, Aedes aegypti, whose evolutionary history and current distribution have been profoundly shaped by humans. We used DNA sequences of four nuclear genes and 1504 single nucleotide polymorphism (SNP) markers developed with restriction-site associated DNA (RAD) sequencing to test the hypothesis that Ae. aegypti originated in Africa, wh

SUBMITTER: Brown JE 

PROVIDER: S-EPMC3946797 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature