Treatment retention among patients randomized to buprenorphine/naloxone compared to methadone in a multi-site trial.

ABSTRACT:

Aims

To examine patient and medication characteristics associated with retention and continued illicit opioid use in methadone (MET) versus buprenorphine/naloxone (BUP) treatment for opioid dependence.

Design, settings and participants

This secondary analysis included 1267 opioid-dependent individuals participating in nine opioid treatment programs between 2006 and 2009 and randomized to receive open-label BUP or MET for 24 weeks.

Measurements

The analyses included measures of patient characteristics at baseline (demographics; use of alcohol, cigarettes and illicit drugs; self-rated mental and physical health), medication dose and urine drug screens during treatment, and treatment completion and days in treatment during the 24-week trial.

Findings

The treatment

SUBMITTER: Hser YI 

PROVIDER: S-EPMC3947022 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature