Inhaled anticoagulation regimens for the treatment of smoke inhalation-associated acute lung injury: a systematic review.

ABSTRACT:

Objective

Inhaled anticoagulation regimens are increasingly being used to manage smoke inhalation-associated acute lung injury. We systematically reviewed published and unpublished preclinical and clinical trial data to elucidate the effects of these regimens on lung injury severity, airway obstruction, ventilation, oxygenation, pulmonary infections, bleeding complications, and survival.

Data sources

PubMed, Scopus, EMBASE, and Web of Science were searched to identify relevant published studies. Relevant unpublished studies were identified by searching the Australian and New Zealand Clinical Trials Registry, World Health Organization International Clinical Trials Registry Platform, Cochrane Library, ClinicalTrials.gov, MINDCULL.com, Current Controlled Trials, and Google.

SUBMITTER: Miller AC 

PROVIDER: S-EPMC3947059 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature