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Dataset Information

Repair of posterior mitral valve prolapse with a novel leaflet plication clip in an animal model.


ABSTRACT:

Objective

Recently, there has been increased interest in minimally invasive mitral valve prolapse repair techniques; however, these techniques have limitations. A new technique was developed for treating mitral valve prolapse that uses a novel leaflet plication clip to selectively plicate the prolapsed leaflet segment. The clip's efficacy was tested in an animal model.

Methods

Yorkshire pigs (n = 7) were placed on cardiopulmonary bypass (CPB), and mitral valve prolapse was created by cutting chordae supporting the P2 segment of the posterior leaflet. Animals were weaned off CPB and mitral regurgitation (MR) was assessed echocardiographically. CPB was reinitiated and the plication clip was applied under direct vision to the P2 segment to eliminate the prolapse. The animals su

SUBMITTER: Feins EN 

PROVIDER: S-EPMC3947119 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature