Temporal trends in phthalate exposures: findings from the National Health and Nutrition Examination Survey, 2001-2010.

ABSTRACT:

Background

Phthalates are ubiquitous environmental contaminants. Because of potential adverse effects on human health, butylbenzyl phthalate [BBzP; metabolite, monobenzyl phthalate (MBzP)], di-n-butyl phthalate [DnBP; metabolite, mono-n-butyl phthalate (MnBP)], and di(2-ethylhexyl) phthalate (DEHP) are being replaced by substitutes including other phthalates; however, little is known about consequent trends in population-level exposures.

Objective

We examined temporal trends in urinary concentrations of phthalate metabolites in the general U.S. population and whether trends vary by sociodemographic characteristics.

Methods

We combined data on 11 phthalate metabolites for 11,071 participants from five cycles of the National Health and Nutrition Examination Survey (2001

SUBMITTER: Zota AR 

PROVIDER: S-EPMC3948032 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature