Pathway based analysis of genes and interactions influencing porcine testis samples from boars with divergent androstenone content in back fat.

ABSTRACT: One of the primary factors contributing to boar taint is the level of androstenone in porcine adipose tissues. A majority of the studies performed to identify candidate biomarkers for the synthesis of androstenone in testis tissues follow a reductionist approach, identifying and studying the effect of biomarkers individually. Although these studies provide detailed information on individual biomarkers, a global picture of changes in metabolic pathways that lead to the difference in androstenone synthesis is still missing. The aim of this work was to identify major pathways and interactions influencing steroid hormone synthesis and androstenone biosynthesis using an integrative approach to provide a bird's eye view of the factors causing difference in steroidogenesis and androstenone biosyn

SUBMITTER: Sahadevan S 

PROVIDER: S-EPMC3948775 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature