Identification of genes regulating growth and fatness traits in pig through hypothalamic transcriptome analysis.

ABSTRACT: Previous studies on Iberian × Landrace (IBMAP) pig intercrosses have enabled the identification of several quantitative trait locus (QTL) regions related to growth and fatness traits; however, the genetic variation underlying those QTLs are still unknown. These traits are not only relevant because of their impact on economically important production traits, but also because pig constitutes a widely studied animal model for human obesity and obesity-related diseases. The hypothalamus is the main gland regulating growth, food intake, and fat accumulation. Therefore, the aim of this work was to identify genes and/or gene transcripts involved in the determination of growth and fatness in pig by a comparison of the whole hypothalamic transcriptome (RNA-Seq) in two groups of phenotypically diver

SUBMITTER: Perez-Montarelo D 

PROVIDER: S-EPMC3949103 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature