Abnormal neural processing during emotional salience attribution of affective asymmetry in patients with schizophrenia.

ABSTRACT: Aberrant emotional salience attribution has been reported to be an important clinical feature in patients with schizophrenia. Real life stimuli that incorporate both positive and negative emotional traits lead to affective asymmetry such as negativity bias and positivity offset. In this study, we investigated the neural correlates of emotional salience attribution in patients with schizophrenia when affective asymmetry was processed. Fifteen patients with schizophrenia and 14 healthy controls were scanned using functional magnetic resonance imaging (fMRI) while performing an emotion judgment task in which two pictures were juxtaposed. The task consisted of responding to affective asymmetry condition (ambivalent and neutral) and affective symmetry conditions (positive and negative), and gro

SUBMITTER: Lee SK 

PROVIDER: S-EPMC3949688 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature