Temporal association in hospitalizations for tuberculosis, invasive pneumococcal disease and influenza virus illness in South African children.

ABSTRACT:

Introduction

The seasonal variability in hospitalization for tuberculosis may in part relate to super-imposed bacterial or predisposing respiratory viral infections. We aimed to study the temporal association between hospitalization for culture-confirmed pulmonary tuberculosis (PTB), invasive pneumococcal disease (IPD) and influenza virus epidemics in South African children.

Methods

We undertook a retrospective analysis which examined seasonal trends, from 2005 to 2008, for hospitalization for culture-confirmed PTB and IPD among children in relation to the influenza epidemics in Soweto, South Africa. Original time-series of the influenza virus epidemics and hospitalization rates for PTB and IPD were decomposed into three components: a trend cycle component, a seasonal compon

SUBMITTER: Dangor Z 

PROVIDER: S-EPMC3950213 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature