Building addressable libraries: the use of "safety-catch" linkers on microelectrode arrays.

ABSTRACT: A "safety-catch" linker strategy has been used to site-selectively cleave and characterize molecules from a microelectrode array. The linkers are attached to the array by means of an ester and contain either a protected amine or protected alcohol nucleophile that can be released using acid generated at the microelectrodes.

SUBMITTER: Bi B 

PROVIDER: S-EPMC3950313 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature