Personality, behavior and environmental features associated with OXTR genetic variants in British mothers.

ABSTRACT:

Background

It is assumed that the oxytocin receptor gene (OXTR) is associated with factors that are related to features of reproduction as well as the currently emerging fields of mood and emotional response.

Methods

We analysed data from over 8000 mothers who participated in the Avon Longitudinal Study of Parents and Children (ALSPAC). We determined reproductive, emotional and personality differences related to the two SNPs rs53576 and rs2254298 of the oxytocin receptor gene to determine whether there was evidence in this population for: (i) associations with emotional and personality differences, and (ii) behavioural or environmental links with these SNPs using a hypothesis free approach with over 1000 types of exposure.

Results

Our analyses of 7723 women showed tha

SUBMITTER: Connelly JJ 

PROVIDER: S-EPMC3951216 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature