Baseline comorbidities in a skin cancer prevention trial in Bangladesh.

ABSTRACT:

Background

Epidemiologic research suggests that increased cancer risk due to chronic arsenic exposure persists for several decades even after the exposure has terminated. Observational studies suggest that antioxidants exert a protective effect on arsenical skin lesions and cancers among those chronically exposed to arsenic through drinking water. This study reports on the design, methods and baseline analyses from the Bangladesh Vitamin E and Selenium Trial (BEST), a population-based chemoprevention study conducted among adults in Bangladesh with visible arsenic toxicity.

Materials and methods

Bangladesh Vitamin E and Selenium Trial is a 2 × 2 full factorial, double-blind, randomized controlled trial of 7000 adults having manifest arsenical skin lesions evaluating the effic

SUBMITTER: Argos M 

PROVIDER: S-EPMC3953314 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature