Risk of multiple myeloma in rheumatoid arthritis: a meta-analysis of case-control and cohort studies.

ABSTRACT:

Objectives

multiple myeloma is a malignant neoplasm of plasma cells mainly affecting elderly patients. Despite the wealth of information available on therapeutic strategies, the etiology and pathogenesis of myeloma remain unclear. In the current study, a meta-analysis was conducted to assess the possible association between rheumatoid arthritis and myeloma.

Methods

a literature search was conducted with PubMed, EMBASE and Web of Science for relevant studies published by December 25, 2013. Additionally, we searched annual meeting abstracts of the American Society of Hematology from 2004 to 2013. Only original studies that investigated the association between rheumatoid arthritis and myeloma were included. In total, 8 case-control and 10 cohort studies were identified for anal

SUBMITTER: Shen K 

PROVIDER: S-EPMC3953405 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature