Magnesium intake, bone mineral density, and fractures: results from the Women's Health Initiative Observational Study.

ABSTRACT:

Background

Magnesium is a necessary component of bone, but its relation to osteoporotic fractures is unclear.

Objective

We examined magnesium intake as a risk factor for osteoporotic fractures and altered bone mineral density (BMD).

Design

This prospective cohort study included 73,684 postmenopausal women enrolled in the Women's Health Initiative Observational Study. Total daily magnesium intake was estimated from baseline food-frequency questionnaires plus supplements. Hip fractures were confirmed by a medical record review; other fractures were identified by self-report. A baseline BMD analysis was performed in 4778 participants.

Results

Baseline hip BMD was 3% higher (P < 0.001), and whole-body BMD was 2% higher (P < 0.001), in women who consumed >422.5 comp

SUBMITTER: Orchard TS 

PROVIDER: S-EPMC3953885 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature