Targeted memory reactivation during slow wave sleep facilitates emotional memory consolidation.

ABSTRACT:

Study objectives

To investigate the mechanisms by which auditory targeted memory reactivation (TMR) during slow wave sleep (SWS) influences the consolidation of emotionally negative and neutral memories.

Design

Each of 72 (36 negative, 36 neutral) picture-location associations were encoded with a semantically related sound. During a subsequent nap, half of the sounds were replayed in SWS, before picture-location recall was examined in a final test.

Setting

Manchester Sleep Laboratory, University of Manchester.

Participants

15 adults (3 male) mean age = 20.40 (standard deviation ± 3.07).

Interventions

TMR with auditory cues during SWS.

Measurements and results

Performance was assessed by memory accuracy and recall response times (RTs). Data were an

SUBMITTER: Cairney SA 

PROVIDER: S-EPMC3954173 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature