Ontology highlight
ABSTRACT: Objective
Early recognition and treatment of febrile children with serious infections (SI) improves prognosis, however, early detection can be difficult. We aimed to validate the predictive rule-in value of the National Institute for Health and Clinical Excellence (NICE) most severe alarming signs or symptoms to identify SI in children.Design, setting and participants
The 16 most severe ("red") features of the NICE traffic light system were validated in seven different primary care and emergency department settings, including 6,260 children presenting with acute illness.Main outcome measures
We focussed on the individual predictive value of single red features for SI and their combinations. Results were presented as positive likelihood ratios, sensitivities and spec
SUBMITTER: Kerkhof E
PROVIDER: S-EPMC3954615 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature