Functional diversity of the microbial community in healthy subjects and periodontitis patients based on sole carbon source utilization.

ABSTRACT: Chronic periodontitis is one of the most common forms of biofilm-induced diseases. Most of the recent studies were focus on the dental plaque microbial diversity and microbiomes. However, analyzing bacterial diversity at the taxonomic level alone limits deeper comprehension of the ecological relevance of the community. In this study, we compared the metabolic functional diversity of the microbial community in healthy subjects and periodontitis patients in a creative way--to assess the sole carbon source utilization using Biolog assay, which was first applied on oral micro-ecology assessment. Pattern analyses of 95-sole carbon sources catabolism provide a community-level phenotypic profile of the microbial community from different habitats. We found that the microbial community in the perio

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC3954802 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature