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Cardiac positron emission tomography enhances prognostic assessments of patients with suspected cardiac sarcoidosis.


ABSTRACT:

Objectives

This study sought to relate imaging findings on positron emission tomography (PET) to adverse cardiac events in patients referred for evaluation of known or suspected cardiac sarcoidosis.

Background

Although cardiac PET is commonly used to evaluate patients with suspected cardiac sarcoidosis, the relationship between PET findings and clinical outcomes has not been reported.

Methods

We studied 118 consecutive patients with no history of coronary artery disease, who were referred for PET, using [(18)F]fluorodeoxyglucose (FDG) to assess for inflammation and rubidium-82 to evaluate for perfusion defects (PD), following a high-fat/low-carbohydrate diet to suppress normal myocardial glucose uptake. Blind readings of PET data categorized cardiac findings as normal

SUBMITTER: Blankstein R 

PROVIDER: S-EPMC3955730 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature