Association between spoligotype-VNTR types and virulence of Mycobacterium bovis in cattle.

ABSTRACT: Mycobacterium bovis is the causative agent of bovine tuberculosis, a disease that affects approximately 5% of Argentine cattle. The aim of this research was to study if it is possible to infer the degree of virulence of different M. bovis genotypes based on scorified observations of tuberculosis lesions in cattle. In this study, we performed association analyses between several parameters with tuberculosis lesions: M. bovis genotype, degree of progression of tuberculosis, and animal age. For this purpose, the genotype was determined by spoligotyping and the degree of bovine tuberculosis gross lesion was quantified with a score based on clinical observations (number, size, and location of granulomas along with histopathologic features). This study was performed with naturally infected cattl

SUBMITTER: Garbaccio S 

PROVIDER: S-EPMC3956505 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature