Discovery of candidate genes for muscle traits based on GWAS supported by eQTL-analysis.

ABSTRACT: Biochemical and biophysical processes that take place in muscle under relaxed and stressed conditions depend on the abundance and activity of gene products of metabolic and structural pathways. In livestock at post-mortem, these muscle properties determine aspects of meat quality and are measurable. The conversion of muscle to meat mimics pathological processes associated with muscle ischemia, injury or damage in humans and it is an economic factor in pork production. Linkage, association, and expression analyses independently contributed to the identification of trait-associated molecular pathways and genes. We aim at providing multiple evidences for the role of specific genes in meat quality by integrating a genome-wide association study (GWAS) for meat quality traits and the detection o

SUBMITTER: Ponsuksili S 

PROVIDER: S-EPMC3957088 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature