Individual differences in attentional bias associated with cocaine dependence are related to varying engagement of neural processing networks.

ABSTRACT: Cocaine and other drug dependencies are associated with significant attentional bias for drug use stimuli that represents a candidate cognitive marker of drug dependence and treatment outcomes. We explored, using fMRI, the role of discrete neural processing networks in the representation of individual differences in the drug attentional bias effect associated with cocaine dependence (AB-coc) using a word counting Stroop task with personalized cocaine use stimuli (cocStroop). The cocStroop behavioral and neural responses were further compared with those associated with a negative emotional word Stroop task (eStroop) and a neutral word counting Stroop task (cStroop). Brain-behavior correlations were explored using both network-level correlation analysis following independent component analys

SUBMITTER: Kilts CD 

PROVIDER: S-EPMC3957107 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature